Addressing the sensing blind spots caused by stimulation artifacts in conventional closed-loop deep brain stimulation (DBS), our team integrates semiconductor with clinical medicine to develop an intelligent DBS system-on-chip (iDBS SoC) embedded with "Synchronized Sample-and-Hold Artifact Blanking (SSAB)" technology (US patent No. US12,616,829B2). iDBS utilizes the Parkinson＇s disease β oscillations as a biomarker to achieve precise treatment and real-time automated feedback stimulation.

This technology develops an autonomous, self-modulating intelligent deep brain stimulation system-on-chip (iDBS SoC). Powered by "Synchronized Sample-and-Hold Artifact Blanking (SSAB)" technology, it achieves microsecond-level synchronized artifact removal by precisely sampling, holding, and blanking at the circuit level. iDBS isolates artifacts before they reach the sensing front-end and overcoming a million-fold voltage disparity, achieving a simultaneous stimulation and sensing design.

The intelligent deep brain stimulation system-on-chip (iDBS SoC) breaks through the limitations of conventional DBS, which cannot perform simultaneous sensing and stimulation. Featuring our US-patented "Synchronized Sample-and-Hold Artifact Blanking (SSAB)" technology, it effectively resolves sensing blind spots. The iDBS system integrates sensing, computation, and stimulation into a single chip for autonomous operation, achieving low power consumption and precise treatment.