Transcranial Temporal Interference Stimulation (tTIS) is a non-invasive deep brain stimulation technique that utilizes high-frequency alternating currents to generate low-frequency interference within the brain, enabling precise modulation of deep neural structures. Our team has developed a functional tTIS hardware device, completed animal studies and safety certification, and has obtained clinical trial approval. We are currently conducting rehabilitation trials in patients with dementia.

Our tTIS device features dual-channel independent frequency control and theta bust stimulation waveform output, enabling non-invasive and rapid neuroplastic effects of deep brain stimulation. Compared to existing prototypes, it offers a portable, clinically applicable design and complies with IEC 60601 medical safety standards. The technology combines depth, selectivity, and safety, showing strong potential for clinical translation and commercialization.

The tTIS technology has strong commercialization potential, targeting patients with dementia, Parkinson’s disease, spinal cord injury, and chronic pain. It can be applied in clinical treatment and remote rehabilitation, offering a cost-effective alternative to surgery and medication. With deep targeting, high safety, and wearable design, the system is well-positioned for regulatory approval and global commercialization through medical partnerships.