• Technical Name
  • Glycan-maskingglycan-unmasking hemagglutinin antigens for universal influenza vaccine development
  • Operator
  • National Tsing Hua University
  • Booth
  • Bio-tech & New Drugs
  • Contact
  • 陳廷軒
  • Email
  • sadam1114@gmail.com
Technical Description The invention provides a glycan-masking and/or glycan-unmasking hemagglutinin, wherein the glycosylation site(s) is added on globular headremoved on stem. The glycan-masking and/or glycan-unmasking hemagglutinin may induce neutralizing antibody against influenza virus,cross-reactive protection against different virus. The invention also provides a method for manufacturing these antigens.
Scientific Breakthrough The invention provides a glycan-masking and/or glycan-unmasking hemagglutinin, wherein the glycosylation site(s) is added on globular headremoved on stem. The glycan-masking and/or glycan-unmasking hemagglutinin may induce neutralizing antibody against influenza virus,cross-reactive protection against different virus. The invention also provides a method for manufacturing these antigens.
Industrial Applicability The market for seasonal influenza vaccines, sized at US$2.8 billion in 2008–2009 across the major markets, not including the potential of pandemic vaccines. The annual rate of influenza vaccine is approximately 12.6. Our invention provides a glycan-masking and/or glycan-unmasking hemagglutinin antigen design, which can be further used for developing “universal influenza vaccines\".
本網站使用您的Cookie於優化網站。繼續瀏覽網站即表示您同意本公司隱私權政策,您可至隱私權政策了解詳細資訊。