Technical Name |
ProDEP: An Automated Platform for Precise Single-Cell Manipulation |
Project Operator |
National Yang Ming Chiao Tung University |
Project Host |
李鎮宜 |
Summary |
ProDEP is the world's first programmable single-cell manipulation platform that integrates Taiwan’s standard CMOS process with AI-based control for precision biomedical applications. By overcoming traditional limitations in standardization and automation, it enables high-precision, label-free, and contactless cell sorting and transport. With patents filed in Taiwan, the US, and Japan, and multiple IEEE publications, ProDEP provides a concrete foundation for next-generation smart medical devices. |
Scientific Breakthrough |
ProDEP integrates standard CMOS processes into cell manipulation chips, enabling non-contact, label-free, single-cell precision control and scalable production. With high-density programmable electrodes and AI image recognition, the chip dynamically reconfigures electric fields for algorithm-driven, multi-cell operations. Full digital logs support data-driven smart cell manufacturing and GMP compliance, promoting standardization and automation of cell processing. |
Industrial Applicability |
ProDEP is a single-cell automated platform built on Taiwan’s semiconductor technology to address biomedical needs. Using proprietary chips and devices, it enables non-contact, label-free cell handling and sorting with traceable cell trajectories and replicable workflows features. It can be applied to cell therapy development, drug testing, regenerative medicine, and training. The goal is to enable decentralized cell preparation and help Taiwan export core smart medical technologies. |
Keyword |
Programmable Dielectrophoresis Single-Cell Manipulation Automated Cell Handling Platform High-Density Electrode Chip Label-Free Cell Sorting Bioelectronic System Precision Medicine Technology Smart Cell Factory Cell Processing Chip GMP-Compatible Cell Processing Module |