Technical Name Pharmaceutical Composition of Carotenoids
Project Operator Fu Jen Catholic University
Project Host 陳炳輝
Summary
This patented technology encapsulates carotenoid and increase its stability, human bioavailability and biological efficiency. Utilizing this technology, Health Ever Bio-Tech Co developed the world’s first ever botanical drug in treating prostate hypertrophy and demonstrated excellent safety profile and clinical efficacy in a phase III clinical trial completed in US and Taiwan in 2017.
Scientific Breakthrough
Although lycopene possesses many biological activities, it is unstable and the low bioavailability (~1%) makes it impossible to develop drugs. A nano microemulsion technology was developed to encapsulate carotenoids for enhancement of stability & bioavailability with excellent safety profile & clinical efficacy being demonstrated in a phase III clinical trial completed in US & Taiwan in 2017.
Industrial Applicability
More than 50% of men above the age of 50 (two hundred million people) have been estimated to suffer from prostate hypertrophy worldwide.  Lasting over a decade, this invention passed phase-3 clinical trial both in Taiwan and USA, demonstrating this invention to be the only botanic drug for prostate hypertrophy treatment. After approval from Taiwan and US FDA, this botanic drug will be sold in the medical market worldwide.
Keyword Lycopene chylomicron Nanoemulsion Botanic drug Benign prostate hyperplasia
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