• Technical Name
  • Targeting enteroviral translation machinery — novel antiviral agentcell line for vaccine production
  • Operator
  • Chang Gung University
  • Booth
  • Online display only
  • Contact
  • 龔俞安
  • Email
  • francess220@gmail.com
Technical Description 1. This technology finds that vsRNA1 can inhibit enterovirus protein synthesis. Therefore, vsRNA1 can be an enterovirus inhibitor for antiviral development. 2. Recombinant peptides derived from FBP1FBP2 affect the enterovirus translation machinery. The technology utilizes recombinant polypeptides to establish vaccine cell lines to improve the virus yields required for vaccine production.
Scientific Breakthrough 1. There are no anti-viral drugs similar to vsRNA1 have been developed. 2. Engineering host cells to establish useful vaccine cell lines, which can increase enterovirus yields for reducing the cost of vaccine production.
Industrial Applicability Enterovirus remains an important issue for emerging viral infections worldwide. The small RNA molecule vsRNA1 will be a potential target for anti-enterovirus drug development. Moreover, the engineered cell lines can increase virus yields for vaccine production,can be applied to virus diagnosis in clinical virology laboratory.