Technical Name Biosensing chip for distinguishing cancer cell location and disease degree
Project Operator National Chung Cheng University
Project Host 王祥辰
Summary
In recent years, the number of people suffering from cancer has been increasing, but the main cause of cancer is that each patient is very different, which makes its pathological mechanism extremely complex and difficult to clarify, which makes the analysis and analysis of cancer add many variables. In the study of cancer cell measurement, traditionally, it is necessary to rely on large instruments to perform analytical calculations and to extend into the cell membrane during the measurement to measure physiological signals. This research hopes to use microelectromechanical technology to integrate photocurrent and impedance measurement combined with the principle of dielectrophoresis on a single chip to achieve the advantages of fast and high sensitivity to establish a set of platforms for measuring cells, and can integrate multiple tiny. The electrode measures a large number of cells on the same substrate without harming the cells.
Scientific Breakthrough
This research hopes to use microelectromechanical technology to integrate photocurrent and impedance measurement combined with the principle of dielectrophoresis on a single chip to achieve the advantages of fast and high sensitivity to establish a set of platforms for measuring cells, and can integrate multiple tiny The electrode measures a large number of cells on the same substrate without harming the cells, and researches and develops a detection technology with simple operation, fast analysis and low cost. The biochip uses dielectrophoresis to gather cancer cells, providing rapid, label-free cancer cell measurement and completing measurement and identification within 13 minutes.
Industrial Applicability
In the future, this technology can be widely used in the detection of various cancer cells. The use of biosensors in cancer detection and monitoring has great potential. Biosensors can be designed to detect emerging cancer biomarkers and determine various targets. Point of drug effectiveness.
Keyword Photoelectrochemical response Dielectrophoretic impedance measurement Esophageal cancer Lung adenocarcinoma Bladder Cancer
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