| Technical Name | A pharmaceutical composition comprising the benzimidazole compounds for use as an antiplatelet or antithrombotic agent, or for use in the treatment of cancer, or cardiovascular and cerebrovascular dis | ||
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| Project Operator | China Medical University | ||
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| Summary | Benzimidazole compounds of formula (I): wherein R1, R2, R3, R4, R5, X, Y, Z1, and Z2 are defined herein. Also disclosed is a pharmaceutical composition comprising the benzimidazole compounds for use as an antiplatelet or antithrombotic agent, or for use in the treatment of cancer, or cardiovascular and cerebrovascular diseases. |
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| Scientific Breakthrough | 本發明為成功開發具有抗癌作用的新穎benzimidazole衍生物，此衍生物不是P-glycoprotein transporter的受質，對多重抗藥性癌細胞株有效，可廣泛應用於癌症藥物治療，此類結構可作用於細胞微管束，抑制癌細胞生長。 |
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| Industrial Applicability | A pharmaceutical composition comprising the benzimidazole compounds for use as an antiplatelet or antithrombotic agent, or for use in the treatment of cancer, or cardiovascular and cerebrovascular diseases. |
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