Technical Name A pharmaceutical composition comprising the benzimidazole compounds for use as an antiplatelet or antithrombotic agent, or for use in the treatment of cancer, or cardiovascular and cerebrovascular dis
Project Operator China Medical University
Summary
Benzimidazole compounds of formula (I): wherein R1, R2, R3, R4, R5, X, Y, Z1, and Z2 are defined herein. Also disclosed is a pharmaceutical composition comprising the benzimidazole compounds for use as an antiplatelet or antithrombotic agent, or for use in the treatment of cancer, or cardiovascular and cerebrovascular diseases.
Scientific Breakthrough
本發明為成功開發具有抗癌作用的新穎benzimidazole衍生物,此衍生物不是P-glycoprotein transporter的受質,對多重抗藥性癌細胞株有效,可廣泛應用於癌症藥物治療,此類結構可作用於細胞微管束,抑制癌細胞生長。
Industrial Applicability
A pharmaceutical composition comprising the benzimidazole compounds for use as an antiplatelet or antithrombotic agent, or for use in the treatment of cancer, or cardiovascular and cerebrovascular diseases.
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