• Technical Name
  • Dengue and Zika virus domain III-flagellin fusion and glycan-masking E antigen for prime-boost vaccine design
  • Operator
  • 生物科技所
  • Booth
  • Online display only
  • Contact
  • 吳夙欽
  • Email
  • scwu@life.nthu.edu.tw
Technical Description Provided is a prime-boost vaccination includes the second-dose booster of four DENV serotype and ZIKV FliC-DIII proteins to enhance the virus-neutralizing antibody titers. The invention also includes the ZIKV E protein ij loop (E-248NHT) mutation by glycan masking to reduce the elicitation of cross-reactive antibodies for DENV and ZIKV infection enhancements.
Scientific Breakthrough Provided is a prime-boost vaccination includes the second-dose booster of four DENV serotype and ZIKV FliC-DIII proteins to enhance the virus-neutralizing antibody titers. The invention also includes the ZIKV E protein ij loop (E-248NHT) mutation by glycan masking to reduce the elicitation of cross-reactive antibodies for DENV and ZIKV infection enhancements.
Industrial Applicability Our invention provides a prime-boost vaccine design including the second-dose booster of four DENV serotype and ZIKV FliC-DIII proteins to enhance the virus-neutralizing antibody titers and protection. Our invention also includes the ZIKV E protein ij loop (E-248NHT) mutation by glycan masking to reduce the elicitation of cross-reactive antibodies for DENV and ZIKV infection enhancements.
本網站使用您的Cookie於優化網站。繼續瀏覽網站即表示您同意本公司隱私權政策,您可至隱私權政策了解詳細資訊。