The chromium-doped zinc gallate, ZnGa2O4:Cr3+, material is viewed as a long-lasting luminescent phosphor which can avoid tissue autofluorescence interference for in vivo imaging detection. The cubic ZGC revealed a specific accumulation in liver0.5 Gy used at the end of X-ray excitation was sufficient for imaging of deep seated hepatic tumors.

The chromium-doped zinc gallate, ZnGa2O4:Cr3+, material is viewed as a long-lasting luminescent phosphor which can avoid tissue autofluorescence interference for in vivo imaging detection. The cubic ZGC revealed a specific accumulation in liver0.5 Gy used at the end of X-ray excitation was sufficient for imaging of deep seated hepatic tumors.

The excellent long-lasting luminescence leads to significantly improve signal-to-noise in bioimaging. Using X-ray source has beyond the limitation of the penetration depth in tissue under in situ external excitation. These advantages let this nano-platform give the precision in diagnosis of diseases, e.g. malignant tumors, in the deep-seated organs in combination of optical navigation surgery.