The novel peptide that gives a second hit on the insulin receptor can be applied for the treatment of diabetes. It can be developed as a unique drug for the control of diabetic complications, the oral replacementcomplementation of insulin,the delay of using injectable insulin therapy. Moreover, it can be directly applied as the main active ingredient of health foodspharmaceuticals.

Based on the concept of target therapy, we select insulin receptor as a targetidentify the novel insulin receptor-targeting peptides from traditional Chinese medicinal herbs. The solid biochemicalstructural biology data have shown that this is the first unique peptide that targets the insulin receptor, gives a second hit on insulin receptor,effectively overcomes insulin resistance.

糖尿病是一種嚴重的代謝性疾病，目前全球約有4億名糖尿病患者，糖尿病照護市場的總值約為5仟億美元。治療糖尿病的最大瓶頸為胰島素抗性及後續糖尿病併發症，如能解決這些問題，將對此一巨大市場提供極具佔有性之方案。目前以添加治療的方式進行臨床試驗，已證實本技術可有效控制糖化血色素，未來具有龐大的產業開發效益。