Technical Name Discoverydevelopment of novel anti-diabetic drug candidate DBPR211 by antagonizing peripheral CB1 receptors
Project Operator National Health Research Institutes
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Summary
DBPR211 is the second generation of CB1 receptor antagonist with peripheral distribution to avoid undesirable central CB1 receptor-induced psychiatric effects as commonly seen in the first generation of CB1 antagonists. DBPR211 is potentselective,it exhibits satisfactory efficacy, pharmacokinetic properties,can be orally absorbed. In obesediabetic mouse models, DBPR211 significa
Scientific Breakthrough
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Industrial Applicability
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