| Technical Name | Development of Dengue Virus Modified Nonstructural Protein 1 Wing Domain VaccineMonoclonal Antibody against Dengue Virus Infection | ||
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| Project Operator | National Cheng Kung University | ||
| Project Host | - | ||
| Summary | In this study, we developed dengue vaccinetherapeutic drug based on modified dengue virus NS1 wing domain (NS1-WD). We found that modified NS1-WD peptide can induce protective antibodies (Abs) against four serotypes of DENV but low cross reactive autoantibodies against host cells. We found that both Abs against modified NS1-WDspecific monoclonal Ab can inhibit not only viral propagation |
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| Scientific Breakthrough | - |
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| Industrial Applicability | - |
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