Technical Name Engineered and clonally selected cell lines for higher virus titer
Project Operator Research Center for Animal Biologics, National Pingtung University of Science and Technology
Project Host 邱明堂
Summary
Our platforms include:1.Cell/Virus clone selection, 2.Expression of virus receptors in cells,3.Blocking cells’ antiviral response, 4.Immortalization of primary cells, and 5.Serum-free suspension cell culture. This can enhance virus titers, vaccine production efficiency, developing new vaccines, and up to industrial scale with vaccine quality and lower costs.
Scientific Breakthrough
By using this technique platform we can improve virus titer and also improve efficiency of vaccine production for 10 to 10000 fords in comparison to current industrial techniques.(Table 2)
Industrial Applicability
This technology was used to develop varieties of animal vaccines as the table 4.
Keyword Cell Virus Antigen Vaccine Bioreactor Cell culture Virus mass production Interferon Suspension culture Gene editing
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