| Technical Name | Palladium pincer complex of normal and abnormal carbene, preparation method for the same and uses thereof | ||
|---|---|---|---|
| Project Operator | National Changhua University of Education | ||
| Project Host | 李漢文 | ||
| Summary | New tridentate N-heterocyclic carbene ligands and their complexes were synthesized. Their biological application in anticancer activities such as TOV21G are tested, showing superior activities compared to cisplatin. |
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| Scientific Breakthrough | The first use of tridentate abnormal NHC complexes of palladium in anticancer activities |
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| Industrial Applicability | The novel palladium complexes with tridentate normal and abnormal carbene ligands can be a applied as potential anti-cancer drugs |
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| Keyword | N-heterocyclic carbene abnormal N-heterocyclic carbene palladium complexes anticancer drugs ovarian cancer tridentate ligand synthesis low toxicity ligand precursor | ||
- leehm@cc.ncue.edu.tw
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