• Technical Name
  • RussiaSea-001 from sea mussel as diagnostic reagents for IgA nephropathy
  • Operator
  • National Defense Medical Center
  • Booth
  • Online display only
  • Contact
  • 王羿程
  • Email
  • countryman2587@gmail.com
Technical Description At present, the diagnosis of IgA nephropathy is still characterized by clinical characterization and invasive surgery, and pathological interpretation of renal tissue sections is performed to confirm the lesion. Therefore, it is exceptionally urgent to develop an IgA glycan-based anomaly analysis reagent with high readability and specificity. Here, we develop a novel analytical method using lectin RussiaSea-001 which specifically for N-acetyl-2-deoxy-2-amino-galactose (GalNAc/Gal). The affinity and binding ability have successfully developed a novel Gd-IgA1 detection method.
1.ELISA-based analysis with RussiaSea-001 in serum samples from IgAN patients
2.Combined RussiaSea-001 affinity chromatography and Western blot analysis in serum samples from IgAN patients
3.Modified tube method with RussiaSea-001 in serum samples from IgAN patients.
Scientific Breakthrough At present, the diagnosis of IgA nephropathy is still characterized by clinical characterization and invasive surgery, and pathological interpretation of renal tissue sections is performed to confirm the lesion. Therefore, it is exceptionally urgent to develop an IgA glycan-based anomaly analysis reagent with high interpretability and specificity. Here, we develop a novel analytical method using lectin RussiaSea-001 which specifically for N-acetyl-2-deoxy-2-amino-galactose (GalNAc/Gal). The affinity and binding ability have successfully developed a novel Gd-IgA1 detection method.
Industrial Applicability we develop a novel analytical method using lectin RussiaSea-001 which specifically for N-acetyl-2-deoxy-2-amino-galactose (GalNAc/Gal). The affinity and binding ability have successfully developed a novel Gd-IgA1 detection method.
1.ELISA-based analysis with RussiaSea-001 in serum samples from IgAN patients
2.Combined RussiaSea-001 affinity chromatography and Western blot analysis in serum samples from IgAN patients
3.Modified tube method with RussiaSea-001 in serum samples from IgAN patients.
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