Technical Name PHARMACEUTICAL COMPOSITIONS CONTAINING BRAZILIN FOR INHIBITING EXPRESSION OF CYTOKINES OF T HELPER CELL TYPE II AND/OR INHIBITING EXPRESSION OF CHEMOKINES AND USES OF THE SAME
Project Operator China Medical University
Project Host
Summary
A pharmaceutical composition for inhibiting the expression of cytokines of T helper cell type II (Th2 cell) and/or inhibiting the expression of chemokines is provided, wherein the pharmaceutical composition comprises an effective amount of an active component, and the active component is selected from a group consisting of a compound of formula (I), pharmaceutically acceptable salts and esters of the compound, and combinations thereof:

Also provided are uses of the compound of formula (I), and/or the pharmaceutically acceptable salts and/or esters thereof in the manufacture of a medicament.
Scientific Breakthrough
A pharmaceutical composition for inhibiting the expression of cytokines of T helper cell type II (Th2 cell) and/or inhibiting the expression of chemokines is provided, wherein the pharmaceutical composition comprises an effective amount of an active component, and the active component is selected from a group consisting of a compound of formula (I), pharmaceutically acceptable salts and esters of the compound, and combinations thereof:

Also provided are uses of the compound of formula (I), and/or the pharmaceutically acceptable salts and/or esters thereof in the manufacture of a medicament.
Industrial Applicability
可開發為氣喘治療新藥或添加於食品中做為保健食品。由於蘇木素為中藥萃取所得的有效單一成分,在市面上對於氣喘治療中藥多為複方,因此可避免不必要的副作用,並食用低劑量就可達到療效。
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