| Technical Name | Establishment of UPLC-MS/MS combined with Core-shell C18 column and QuEchERS method for rapid determination of heterocyclic amines (HAs) in foodstuffs | ||
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| Project Operator | National Yang-Ming University/China Medical University | ||
| Project Host | 楊登傑/江舟峰 | ||
| Summary | UPLC-MS/MS with Core-shell C18 column was used to develop a high-sensitivity and rapid method to simultaneously determine 22 of HAs in 15 min (it is currently the fastest method to detect the most HAs). In addition, QuEChERS was used to establish rapid extraction conditions (completed in 30 min) for the HAs of the nine major food matrices (currently most). The results were in line with the TFDA regulations, and could be routinely used for rapid monitoring of HAs in foodstuffs. |
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| Scientific Breakthrough | UPLC-MS/MS with Core-shell C18 column was used to develop a high-sensitivity and rapid method to simultaneously determine 22 of HAs in 15 min (it is currently the fastest method to detect the most HAs). QuEChERS was used to establish rapid extraction conditions (completed in 30 min) for the HAs of the nine food matrices (currently most). These developed methods could be used for rapid monitoring of HAs in food. |
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| Industrial Applicability | UPLC-MS/MS with Core-shell C18 column was used to develop a high-sensitivity and rapid method to simultaneously determine 22 of HAs in 15 min (it is currently the fastest method to detect the most HAs). QuEChERS was used to establish rapid extraction conditions (completed in 30 min) for the HAs of the nine food matrices (currently most). These developed methods could be routinely used for rapid monitoring of HAs in foodstuffs. |
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| Keyword | Heterocyclic amine UPLC MS/MS Core shell column QuEChERS Food matrix Rapid Analysis Extraction High sensetivity | ||
| Notes | |||
- Contact
- djyang1@gmail.com
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