Technical Name Immunoassay for A Newly Verified Oral Cancer Biomarker
Project Operator Chang Gung University
Project Host 余兆松
Immunoassays for quantifying a newly verified oral cancer biomarker “OCBM-1” in saliva specimens. Including two platforms: ELISA Kitcolloidal-gold based strip assay, which provides quantitativesemi-quantitative amounts of OCBM-1, respectively. Now the two products are at pilot production stage, which will be soon applied for pre-clinical verificationclinical validation.
Scientific Breakthrough
1.	No routine biomarker test for oral cancer applied in clinical setting currently. Therefore, application of OCBM-1 will be beneficial for early detection of oral cancer.
2.	OCBM-1 is a newly verified salivary biomarker,no OCBM-1-related IVDinternational standard in the world. All the materials in the immunoassay are developedproduced by ourselves in Taiwan.
Industrial Applicability
ELISA Kitcolloidal-gold based strip assay are common immunoassay platforms for protein measurement in clinical test. In this case, materials including antibodies, standard proteins,reagents were generated SOPs for large-scale productionquality control were established. The pipeline could be applied for developing immunoassays for other candidate protein biomarkers.
Keyword Oral cancer Biomarker Saliva Salivary protein Oral mucosal screening Oral screening, ELISA Immunoassay Rapid test Strip test
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