Technical Description |
Vaccination is the most effective way to prevent influenza viruses infection. The egg-based production method has many drawbacks, we established baculovirus-based VLPs expression platform for H7N9 VLPs production, purify the VLPs satisfied with FDA regulation,improved its immunogenicity to the same level compared with H7N9 whole virus vaccine. |
Scientific Breakthrough |
Vaccination is the most effective way to prevent influenza viruses infection. The egg-based production method has many drawbacks, we established baculovirus-based VLPs expression platform for H7N9 VLPs production, purify the VLPs satisfied with FDA regulation,improved its immunogenicity to the same level compared with H7N9 whole virus vaccine. |
Industrial Applicability |
In order to providing safer quality of influenza vaccineimproving its immune effect, the virus-like particle influenza vaccine platform can significantly reduce the cost (no need for high-risk biosafety level IIIII production plants)also be used for seasonal influenza vaccine production as well as other human infectious diseases. |