• Technical Name
  • Influenza virus-like particle vaccine production using baculovirus expression system
  • Operator
  • National Health Research Institutes
  • Booth
  • Online display only
  • Contact
  • 胡勇誌
  • Email
  • alanhu@nhri.edu.tw
Technical Description Vaccination is the most effective way to prevent influenza viruses infection. The egg-based production method has many drawbacks, we established baculovirus-based VLPs expression platform for H7N9 VLPs production, purify the VLPs satisfied with FDA regulation,improved its immunogenicity to the same level compared with H7N9 whole virus vaccine.
Scientific Breakthrough Vaccination is the most effective way to prevent influenza viruses infection. The egg-based production method has many drawbacks, we established baculovirus-based VLPs expression platform for H7N9 VLPs production, purify the VLPs satisfied with FDA regulation,improved its immunogenicity to the same level compared with H7N9 whole virus vaccine.
Industrial Applicability In order to providing safer quality of influenza vaccineimproving its immune effect, the virus-like particle influenza vaccine platform can significantly reduce the cost (no need for high-risk biosafety level IIIII production plants)also be used for seasonal influenza vaccine production as well as other human infectious diseases.
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