Technical Name Synthesis of the Heparin-Based Anticoagulant Drug Fondaparinux
Project Operator Genomics Research Center, Academia Sinica
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Summary
The present invention is made up of commercially available cheap monosaccharides as starting materials, introducing the concept of common intermediates, one-pot synthesis, special protecting group combination,stereospecific control,thus, the 32 synthetic steps are effective synthesis of the target product Fondaparinux. We have adjusted the reaction reagentsreaction conditions, so th
Scientific Breakthrough
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Industrial Applicability
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