Technical Name Multiscale Bio-Imaging Technology
Project Operator National Tsing Hua University
Project Host 江安世
Summary
The developed multiscale microscopy is a patented new technology for super-resolution large-field imaging. The system includes con-shell illumination microscopy, single-molecule localization algorithm,automated tissue sectioning. Combining with FocusClear tissue clearing, our technology can analyze spatial distribution of any proteins of interest within an intact tissue such as brain/tumor.
Scientific Breakthrough
Over 95 current super-resolution microscopy can only focus on single-cell level imaging, which cannot be used in large tissue, also very expansive. Our newly patented super-resolution large-field imaging system can work independentlyeasily integrated onto regular florescent microscopy. Work with sample clearing methodsautomated imaging/sectioning system, multiscale bio-images in one spec
Industrial Applicability
Multiscale bio-imaging system can be applied in visualizing various biology in 3D specimen massively. Users can also apply it on to ultra-high throughput, super-resolution pathology. With AI aid data evaluation, this method can augment the precision of clinical decision,pave the way to a new era toward precision medicine.
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