Technical Name Probing and manipulation of cell surface receptors with molecular scaffold
Project Operator National Tsing Hua University
Project Host 王聖凱
Summary
Use synthetic biomolecule as scaffold to control ligand position at nanometer scale to probe and manipulate cell surface receptors
Scientific Breakthrough
Controlling the spatial presentation of ligands (drug molecules) at nanometer scale through modular assembly of synthetic molecular scaffold.
Industrial Applicability
Change the design and the use of drugs targeting cell surface receptors.
Keyword receptor G protein-coupled receptor drug discovery molecular scaffold multivalent nanotechnology peptide macromolecule biomolecule membrane protein
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