Technical Name High Efficiency on Fixation of CO2Synthesis of Carboxylic acidsEpoxy Derivatives via Transition-Metal Catalysis
Project Operator National Tsing Hua University
Project Host 談駿嵩
"1. An iron-catalyzed hygromagnesiation of alkynes with Grignard reagentsfixation of CO2 for the synthesis of vinylic acids was demonstrated. This methodology features good to excellent yield, high regioselectivity,broad functional group tolerance. On the basis of literature report, the products diarylvinylic acids are bioactive. One of anticancer drugs, HIF-1, can also be synthesized th
Scientific Breakthrough
Industrial Applicability
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