In this technology, a series of potent MOR/NOP agonists has been developed, which demonstrated potent antinociception in tail flick and cancer pain mouse models with fewer side-effects in respiratory suppression, heart rate decreasing, and constipation models than morphine.

1. A first-in-calss pain-killer with low adverse-effects.
2. A MOR/NOP dual and biased-agonist, which possesses a new mode-of-action.
3. A series of patentable small molecules with novel structural scaffold.

A fast painkiller
 -The onset time of this drug is within ten minutes after subcutaneous injection.
Low addiction
 -The NOP activation of this drug reduces addiction.
Slight affecting in the digestive system
 - This drug did not cause constipation.
High level of safety
 -This drug caused low and short-term effects on lung and heart function.